CHLORIDE CHANNEL-2 GENE (CLC2) MAPS TO CHROMOSOME-16 OF THE MOUSE, EXTENDING A REGION OF CONSERVED SYNTENY WITH HUMAN-CHROMOSOME-3Q

被引:4
作者
LENGELING, A
GRONEMEIER, M
RONSIEK, M
THIEMANN, A
JENTSCH, TJ
JOCKUSCH, H
机构
[1] UNIV BIELEFELD,DEV BIOL UNIT,D-33501 BIELEFELD,GERMANY
[2] UNIV HAMBURG,CTR MOLEC NEUROBIOL,D-20246 HAMBURG,GERMANY
关键词
D O I
10.1017/S0016672300034522
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The Clc2 gene of the mouse codes for the ubiquitously expressed chloride channel ClC-2, a member of a family of at least seven voltage gated chloride channels, some of which are implicated in hereditary diseases. Using a mouse interspecies back-cross panel, we have mapped Clc2 to Chr 16, proximal to the somatostatin gene Smst, extending a region of documented conserved synteny to human Chr 3q.
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页码:175 / 178
页数:4
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