REPEATED MEASUREMENTS OF PULMONARY-FUNCTION FOLLOWING SPINAL-CORD INJURY

被引：43

作者：

BLUECHARDT, MH

WIENS, M

THOMAS, SG

PLYLEY, MJ

机构：

[1] Faculty of Physical Activity Studies, University of Regina, Regina, SK

[2] Department of Physiotherapy, Lyndhurst Hospital, Toronto, ON

[3] Department of Rehabilitation Medicine, University of Toronto, Toronto, ON

[4] School of Physical and Health Education, University of Toronto, Toronto, ON

来源：

PARAPLEGIA | 1992年 / 30卷 / 11期

关键词：

SPINAL CORD INJURY; LUNG VOLUME MEASUREMENTS; RESPIRATORY FUNCTION TESTS;

D O I：

10.1038/sc.1992.148

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Twelve subjects (11 males, 1 female) with complete spinal cord lesion (level of lesion ranging from C4 to T10), with a mean age of 23.5 years participated in pulmonary function testing (PFT). Inspiratory and expiratory flow measurements were made at 2-month intervals from 25 to 351 days post injury. The values were interpolated and extrapolated to common dates to facilitate comparison. The effect of time on pulmonary function was determined by a repeated measures ANOVA. Forced expiratory volume in 1 second (FEV1.0) significantly increased during the course of the study (40%, p < 0.05), but increases in forced vital capacity (FVC) (32.5%) and maximal voluntary ventilation (MVV) (16%) were not statistically significant. Lesion level was found to be correlated (Spearman Product Moment Correlation) with pulmonary function if a single measure was made (r = 0.55 to 0.73), but emerged as a stronger predictor if the average of several repeated PFTs was correlated with lesion level (r = 0.74 to 0.84). In addition, lesion level was not correlated with the amount of improvement attained during the time period studied. We conclude that the time course of recovery of pulmonary function is variable between individuals with spinal cord injuries and can only be weakly predicted by knowledge of the initial value and the lesion level.

引用

页码：768 / 774

页数：7

共 12 条

[1]

Axen K., Pineda H., Shunfenthal I., Haas F., Diaphragmatic function following cervical cord injury: Neurally mediated improvement, Arch Phys Med Rehabil, 66, pp. 219-222, (1985)

[2]

Carter R.E., Experiences with high tetraplegics, Paraplegia, 17, pp. 140-146, (1970)

[3]

Cherniack R.M., Raber M.D., Normal standards for ventilatory function using an automated wedge spirometer, Am Rev Resp Dis, 106, pp. 38-46, (1972)

[4]

Haas F., Azen K., Pineda H., Gandino D., Haas A., Temporal pulmonary function changes in cervical cord injury, Arch Phys Med Rehabil, 66, pp. 139-144, (1985)

[5]

Haas A., Lowman E.W., Bergofsky E.H., Impairment of respiration after spinal cord injury, Arch Phys Med Rehabil, 46, pp. 399-405, (1965)

[6]

Ledsome J.R., Sharp J.M., Pulmonary function in acute cervical cord injury, Am Rev Respir Dis, 124, pp. 41-44, (1981)

[7]

McMichan J.C., Michel L., Westbrook P.R., Pulmonary dysfunction following traumatic quadriplegia, JAMA, 243, pp. 528-531, (1980)

[8]

Ohry A., Molho M., Rozin R., Alterations of pulmonary function in spinal cord injured patients, Paraplegia, 13, pp. 101-108, (1975)

[9]

Knudson R.J., Slatin R.C., Lebowitz M.D., Burrows B., The maximal expiratory flow-volume curve - normal standards, variability and effects of age, Am Rev Respir Dis, 113, pp. 587-600, (1976)

[10]

Pedhauser E.J., Multiple Regression in Behavioural Research, (1982)

← 1 2 →