SYNTHESIS OF THE TETRASACCHARIDE REPEATING UNIT OF THE ANTIGEN FROM KLEBSIELLA TYPE-20

被引：2

作者：

DAS, SK ^{[1
]}

ROY, N ^{[1
]}

机构：

[1] INDIAN ASSOC CULTIVAT SCI,DEPT BIOL CHEM,CALCUTTA 700032,W BENGAL,INDIA

来源：

CARBOHYDRATE RESEARCH | 1995年 / 271卷 / 02期

关键词：

SYNTHESIS; TETRASACCHARIDE REPEATING UNIT; KLEBSIELLA TYPE 20;

D O I：

10.1016/0008-6215(95)00064-Z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Starting from D-mannose, D-galactose and D-glucuronolactone, two disaccharide blocks, namely methyl 4,6-di-O-benzyl-2-O-(2,3,4,6-tetra-O-benzyl-beta-D-galactopyranosyl)-alpha-D-mannopyranoside, acting as acceptor, and ethyl 4,6-di-O-acetyl-2-O-allyl-3-O-(methyl 2,3,4-tri-O-acetyl-beta-D-glucopyranosyluronate)-1-thio-beta-D-galactopyranoside, acting as donor, were synthesised. The two disaccharides were then allowed to react to give, after deprotection, methyl 2-O-beta-D-galactopyranosyl-3-O-(3-O-beta-D-glucopyranosyluronic acid-alpha-D-galactopyranosyl)-alpha-D-mannopyranoside which is the methyl glycoside of the tetrasaccharide repeating unit of the said antigen.

引用

页码：177 / 183

页数：7

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