DIFFERENTIATION OF ENANTIOTOPIC CARBONYL GROUPS BY THE HORNER-WADSWORTH-EMMONS REACTION

被引：78

作者：

TANAKA, K

OHTA, Y

FUJI, K

TAGA, T

机构：

[1] KYOTO UNIV,INST CHEM RES,UJI,KYOTO 611,JAPAN

[2] KYOTO UNIV,FAC PHARMACEUT SCI,SAKYO KU,KYOTO 606,JAPAN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 25期

关键词：

D O I：

10.1016/S0040-4039(00)60618-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A chiral phosphonoacetate 2 differentiates the enantiotopic carbonyl groups in an alpha-diketone 5 to afford the Z-olefin 6 in high yield and ee. The absolute stereochemistry of 6 was determined by X-ray analysis of 8 derived from 6.

引用

页码：4071 / 4074

页数：4

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