Mapping of sequences selectively binding to nuclear matrix on human chromosome 19

被引:0
|
作者
Nikolaev, LG
Tsogtkhishig, T
Akopov, SB
Sverdlov, ED
机构
来源
BIOORGANICHESKAYA KHIMIYA | 1995年 / 21卷 / 12期
关键词
human chromosome 19; nuclear matrix; matrix attachment regions; functional mapping;
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学科分类号
摘要
A plasmid library (400 clones) of the human chromosome 19 sequences selectively binding to nuclear matrix was obtained and characterized. Approximately 50% clones contained DNA sequences specific for human chromosome 19. Over 90% of these sequences represented matrix attachment regions (MARs). Eight MARs were localized to the chromosome 19 physical map.
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页码:954 / 958
页数:5
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