ULTRASTRUCTURAL-CHANGES IN RAT MAMMOTROPES FOLLOWING INCUBATION WITH DOPAMINE

被引：2
作者：
JONEJA, M [1 ]
REIFEL, CW [1 ]
MURPHY, ML [1 ]
SHIN, SH [1 ]
机构：
[1] QUEENS UNIV, DEPT PHYSIOL, KINGSTON K7L 3N6, ONTARIO, CANADA
来源：
EXPERIENTIA | 1993年 / 49卷 / 10期
关键词：
PITUITARY; ADENOHYPOHYSIS; MAMMOTROPE; DOPAMINE; PROLACTIN;
D O I：
10.1007/BF01952593
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Cultured mammotropes incubated with dopamine for one hour exhibited changes in ultrastructure indicative of actively depressed biosynthetic and secretory activity. Peripheral relocation of rough endoplasmic reticulum appeared to create a barrier to secretory granule release by exocytosis. A decrease in the numbers of secretory granules indicated a decrease in prolactin production and enhanced lysosomal activity.
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收藏
页码：836 / 839
页数：4
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