COMPARISON OF THE PRESSOR EFFECTS OF ANGIOTENSIN-II AND ANGIOTENSIN-III IN THE ROSTRAL VENTROLATERAL MEDULLA

被引：17

作者：

SASAKI, S ^{[1
]}

LI, YW ^{[1
]}

DAMPNEY, RAL ^{[1
]}

机构：

[1] UNIV SYDNEY, DEPT PHYSIOL, SYDNEY, NSW 2006, AUSTRALIA

来源：

BRAIN RESEARCH | 1993年 / 600卷 / 02期

基金：

英国医学研究理事会;

关键词：

ANGIOTENSIN; AMASTATIN; BESTATIN; ROSTRAL VENTROLATERAL MEDULLA; BLOOD PRESSURE;

D O I：

10.1016/0006-8993(93)91393-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Microinjection of angiotensin II and III into the rostral ventrolateral medulla of anesthetized barodenervated rabbits elicited in both cases pressor responses, which were of similar magnitude and time course. The responses to angiotensin II and III were either unchanged or increased in the presence of compounds which inhibit their degradation to shorter length peptides. The results indicate that both angiotensin peptides are independently capable of eliciting pressor responses in the rostral ventrolateral medulla.

引用

页码：335 / 338

页数：4

共 22 条

[1] ANGIOTENSIN RECEPTOR-BINDING AND PRESSOR EFFECTS IN CAT SUBRETROFACIAL NUCLEUS [J].

ALLEN, AM ;

DAMPNEY, RAL ;

MENDELSOHN, FAO .

AMERICAN JOURNAL OF PHYSIOLOGY, 1988, 255 (05) :H1011-H1017

[2]

ANDREATTA SH, 1988, HYPERTENSION, V11, P163

[3] MEDULLARY BASAL SYMPATHETIC TONE [J].

CALARESU, FR ;

YARDLEY, CP .

ANNUAL REVIEW OF PHYSIOLOGY, 1988, 50 :511-524

[4] ANATOMICAL EVIDENCE THAT HYPERTENSION ASSOCIATED WITH THE DEFENSE REACTION IN THE CAT IS MEDIATED BY A DIRECT PROJECTION FROM A RESTRICTED PORTION OF THE MIDBRAIN PERIAQUEDUCTAL GREY TO THE SUBRETROFACIAL NUCLEUS OF THE MEDULLA [J].

CARRIVE, P ;

BANDLER, R ;

DAMPNEY, RAL .

BRAIN RESEARCH, 1988, 460 (02) :339-345

[5]

DAMPNEY R, 1990, NEWS PHYSIOL SCI, V5, P63

[6] AFFERENT CONNECTIONS AND SPINAL PROJECTIONS OF THE PRESSOR REGION IN THE ROSTRAL VENTROLATERAL MEDULLA OF THE CAT [J].

DAMPNEY, RAL ;

CZACHURSKI, J ;

DEMBOWSKY, K ;

GOODCHILD, AK ;

SELLER, H .

JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 1987, 20 (01) :73-86

[7] ORIGIN OF TONIC GABAERGIC INPUTS TO VASOPRESSOR NEURONS IN THE SUBRETROFACIAL NUCLEUS OF THE RABBIT [J].

DAMPNEY, RAL ;

BLESSING, WW ;

TAN, E .

JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 1988, 24 (03) :227-239

[8] VASOPRESSOR NEURONS IN THE ROSTRAL VENTROLATERAL MEDULLA OF THE RABBIT [J].

DAMPNEY, RAL ;

GOODCHILD, AK ;

TAN, E .

JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM, 1985, 14 (03) :239-254

[9] EFFECTS OF AMINOPEPTIDASE INHIBITION ON THE HALF-LIVES OF [I-125] ANGIOTENSINS IN THE CEREBROVENTRICLES OF THE RAT [J].

DEWEY, AL ;

WRIGHT, JW ;

HANESWORTH, JM ;

HARDING, JW .

BRAIN RESEARCH, 1988, 448 (02) :369-372

[10] ANGIOTENSIN RECEPTIVE NEURONS IN SUBFORNICAL ORGAN - STRUCTURE-ACTIVITY RELATIONS [J].

FELIX, D ;

SCHLEGEL, W .

BRAIN RESEARCH, 1978, 149 (01) :107-116

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