THERAPY FOR MULTIPLE-SCLEROSIS

被引：11
作者：
WEINER, HL
HOHOL, MJ
KHOURY, SJ
DAWSON, DM
HAFLER, DA
机构：
[1] BRIGHAM & WOMENS HOSP,CTR NEUROL DIS,MULTIPLE SCLEROSIS UNIT,BOSTON,MA 02115
[2] HARVARD UNIV,SCH MED,BOSTON,MA
来源：
NEUROLOGIC CLINICS | 1995年 / 13卷 / 01期
关键词：
D O I：
10.1016/S0733-8619(18)30066-5
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Multiple sclerosis is hypothesized to be a cell-mediated autoimmune disease directed against central nervous system myelin. Immunotherapy is directed at decreasing the autoimmune response using both specific and nonspecific modulation of the immune system in an attempt to halt accumulation of disability. Symptomatic therapy may also help multiple sclerosis patients.
引用
收藏
页码：173 / 196
页数：24
相关论文
共 92 条
  • [1] INTRAVENOUS IMMUNOGLOBULIN TREATMENT OF EXPERIMENTAL T-CELL-MEDIATED AUTOIMMUNE-DISEASE - UP-REGULATION OF T-CELL PROLIFERATION AND DOWN-REGULATION OF TUMOR-NECROSIS-FACTOR-ALPHA SECRETION
    ACHIRON, A
    MARGALIT, R
    HERSHKOVIZ, R
    MARKOVITS, D
    RESHEF, T
    MELAMED, E
    COHEN, IR
    LIDER, O
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1994, 93 (02) : 600 - 605
  • [2] ACHIRON A, 1992, ARCH NEUROL-CHICAGO, V449, P1233
  • [3] ANTIGEN-DRIVEN TISSUE-SPECIFIC SUPPRESSION FOLLOWING ORAL TOLERANCE - ORALLY-ADMINISTERED MYELIN BASIC-PROTEIN SUPPRESSES PROTEOLIPID PROTEIN-INDUCED EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS IN THE SJL MOUSE
    ALSABBAGH, A
    MILLER, A
    SANTOS, LMB
    WEINER, HL
    [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1994, 24 (09) : 2104 - 2109
  • [4] ALSABBAGH A, 1994, NEUROLOGY
  • [5] [Anonymous], 1990, ANN NEUROL, V27, P591
  • [6] ANTEL JP, 1986, J IMMUNOL, V137, P137
  • [7] INHIBITION OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS BY AN ANTIBODY TO THE INTERCELLULAR-ADHESION MOLECULE ICAM-1
    ARCHELOS, JJ
    JUNG, S
    MAURER, M
    SCHMIED, M
    LASSMANN, H
    TAMATANI, T
    MIYASAKA, M
    TOYKA, KV
    HARTUNG, HP
    [J]. ANNALS OF NEUROLOGY, 1993, 34 (02) : 145 - 154
  • [8] INTERFERON-BETA IN MULTIPLE-SCLEROSIS
    ARNASON, BGW
    [J]. NEUROLOGY, 1993, 43 (04) : 641 - 643
  • [9] A RANDOMIZED, CONTROLLED TRIAL OF CORTICOSTEROIDS IN THE TREATMENT OF ACUTE OPTIC NEURITIS
    BECK, RW
    CLEARY, PA
    ANDERSON, MM
    KELTNER, JL
    SHULTS, WT
    KAUFMAN, DI
    BUCKLEY, EG
    CORBETT, JJ
    KUPERSMITH, MJ
    MILLER, NR
    SAVINO, PJ
    GUY, JR
    TROBE, JD
    MCCRARY, JA
    SMITH, CH
    CHROUSOS, GA
    THOMPSON, HS
    KATZ, BJ
    BRODSKY, MC
    GOODWIN, JA
    ATWELL, CW
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1992, 326 (09) : 581 - 588
  • [10] OPTIC NEURITIS TREATMENT TRIAL - ONE-YEAR FOLLOW-UP RESULTS
    BECK, RW
    CLEARY, PA
    [J]. ARCHIVES OF OPHTHALMOLOGY, 1993, 111 (06) : 773 - 775
12345678910