ELECTROPHILIC SUBSTITUTION-REACTIONS OF 1,1-DIFLUORO-1H-CYCLOPROPABENZENE

被引：5
作者：
NEIDLEIN, R
KOHL, M
机构：
[1] Pharmazeutisch-Chemisches Institut, Universität Heidelberg, Heidelberg, D-6900
来源：
HELVETICA CHIMICA ACTA | 1990年 / 73卷 / 05期
关键词：
D O I：
10.1002/hlca.19900730529
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Electrophilic Substitution Reactions of 1,1‐;Difluoro‐1H‐cyclopropabenzene 1,1‐Difluoro‐1H‐cyclopropabenzene (1) can be deprotonated with strong bases at C(2). The resulting 1,1‐di‐fluoro‐2‐lithio‐1H‐cyclopropabenzene (2) reacts with electrophiles to form C(2)‐substituted derivatives of 1. The Diels‐Alder reactions with electron‐poor dienes, characteristic for 1H‐cyclopropabenzene, do not occur with the 1,1‐difluoro analogue 1. Copyright © 1990 Verlag GmbH & Co. KGaA, Weinheim
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页码：1497 / 1503
页数：7
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