SUCCESSFUL MULTIMODAL THERAPY WITH CHEMOTHERAPY AND SURGERY FOR BILATERAL PULMONARY METASTASES SECONDARY TO HEPATOBLASTOMA

被引:2
作者
IWAFUCHI, M
OHSAWA, Y
UCHIYAMA, M
HIROTA, M
NAITOH, M
SAITOH, H
ODA, Y
ABE, T
ASAMI, K
机构
[1] Department of Pediatric Surgery, Niigata University Hospital
关键词
HEPATOBLASTOMA; BILATERAL PULMONARY METASTASES; MULTIDRUG CHEMOTHERAPY; SURGERY;
D O I
10.1007/BF00183922
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Two children with hepatoblastoma and bilateral pulmonary metastases were effectively treated with an aggressive combination of chemotherapy and surgery. Chemotherapeutic agents included cyclophosphamide, vincristine, THP-adriamycin, and cis-platinum. The pulmonary metastases were temporarily responsive to a regimen of these agents, recurred, and were subsequently resected without further recurrence. Such multimodal therapy is advocated for the treatment of pulmonary metastases secondary to hepatoblastoma.
引用
收藏
页码:134 / 136
页数:3
相关论文
共 9 条
[1]  
Andrassy R.J., Brennan L.P., Siegel M.M., Weitzman J.J., Siegel S.E., Stanley P., Mahour G.H., Preoperative chemotherapy for hepatoblastoma in children, J Pediatr Surg, 15, pp. 517-522, (1980)
[2]  
Evans A.E., Land V.J., Newton W.A., Randolph J.G., Sather H.N., Tefft M., Combination chemotherapy (vincristine, adriamycin, cyclophosphamide and 5-fluorouracil) in the treatment of children with malignant hepatoma, Cancer, 50, pp. 821-826, (1982)
[3]  
Ikeda K., Suita S., Nakagawara A., Takabayashi K., Preoperative chemotherapy for initially unresectable hepatoblastoma in children, survival in two cases, Arch Surg, 114, pp. 203-207, (1979)
[4]  
Iwafuch M., Muto T., Ohsawa Y., Yamashita Y., Matsuda Y., Yoshida K., Hepatoma in children — A clinical analysis of 15 cases, The Japanese Journal of Surgery, 11, pp. 454-459, (1981)
[5]  
Ogita S., Tokiwa K., Takahashi T., Combination chemotherapy for unresectable hepatoblastoma in children, Jpn J Surg, 17, pp. 21-27, (1987)
[6]  
Pierro A., Langevin A., Filler R.M., Liu P., Phillips M.J., Greenberg M.J., Preoperative chemotherapy in unresectable hepatoblastoma, J Pediatr Surg, 24, pp. 24-29, (1989)
[7]  
Randolph J., Chanda R., Leiken S., Malignant liver tumors in infants and children, World J Surg, 4, pp. 71-82, (1980)
[8]  
Sawaguchi S., Kaneko M., Uchino J., Takada T., Iwafuchi M., Matsuyama S., Takahashi H., Nakajo T., Hoshi Y., Okabe I., Yokoyoma J., Nishihira H., Sasaki S., Sakurai M., Sawada T., Nagahara N., Tsuchida Y., Treatment of advanced neuroblastoma with emphasis on intensive induction chemotherapy. A report from the Study Group of Japan, Cancer, 66, pp. 1879-1887, (1990)
[9]  
Takayama T., Makuuchi M., Takayasu K., Thai B.L., Ohyama H., Yamazaki S., Hasegawa H., Resection after intraarterial chemotherapy of a hepatoblastoma originating in the caudate lobe, Surgery, 107, pp. 231-235, (1990)