POSSIBLE INDUCTION OF INTERCELLULAR-ADHESION MOLECULE-1 (ICAM-1) EXPRESSION ON ENDOTHELIAL-CELLS BY PLATELET-ACTIVATING-FACTOR (PAF)

被引：0

作者：

CHIHARA, J

MARUYAMA, I

YASUBA, H

YASUKAWA, A

YAMAMOTO, T

KURACHI, D

MOURI, T

SEGUCHI, M

NAKAJIMA, S

机构：

[1] KAGOSHIMA UNIV,DEPT INTERNAL MED 3,KAGOSHIMA 890,JAPAN

[2] KYOTO UNIV,DEPT INTERNAL MED 2,CHEST DIS RES INST,KYOTO 606,JAPAN

来源：

JOURNAL OF LIPID MEDIATORS | 1992年 / 5卷 / 02期

关键词：

PAF; PLATELET FACTOR-IV; INTERLEUKIN-1; INTERCELLULAR ADHESION MOLECULE-1; BRONCHIAL ASTHMA; ENDOTHELIAL CELL;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We demonstrated that PAF and IL-1 markedly induce ICAM-1 expression on endothelial cells. These findings suggest that PAF not only modulates inflammation by the attraction and activation of eosinophils or by platelet activation, but also intensifies such phenomena by induction of ICAM-1 expression on endothelial cells.

引用

页码：159 / 162

页数：4

共 10 条

[1] INTERACTION OF PLATELET-ACTIVATING FACTOR WITH INTERFERON-GAMMA IN THE STIMULATION OF INTERLEUKIN-1 PRODUCTION BY HUMAN MONOCYTES [J].