VALIDATION OF MATHEMATICAL-MODELS OF COMPLEX ENDOCRINE-METABOLIC SYSTEMS - A CASE-STUDY ON A MODEL OF GLUCOSE REGULATION

被引：76
作者：
COBELLI, C [1 ]
MARI, A [1 ]
机构：
[1] CNR,LADSEB,CORSO STATI UNIT 4,I-35100 PADUA,ITALY
来源：
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING | 1983年 / 21卷 / 04期
关键词：
D O I：
10.1007/BF02442625
中图分类号：
TP39 [计算机的应用];
学科分类号：
081203 ; 0835 ;
摘要：
引用
收藏
页码：390 / 399
页数：10
相关论文
共 14 条
[1]  
BERGMAN RN, 1980, FED PROC, V39, P110
[2]  
BERGMAN RN, 1980, IDENTIFICATION SYSTE, V2, P883
[3]   MODELING AND IDENTIFICATION OF METABOLIC SYSTEMS [J].
CARSON, ER ;
COBELLI, C ;
FINKELSTEIN, L .
AMERICAN JOURNAL OF PHYSIOLOGY, 1981, 240 (03) :R120-R129
[4]   EVALUATION OF PORTAL PERIPHERAL ROUTE AND OF ALGORITHMS FOR INSULIN DELIVERY IN THE CLOSED-LOOP CONTROL OF GLUCOSE IN DIABETES - A MODELING STUDY [J].
COBELLI, C ;
RUGGERI, A .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1983, 30 (02) :93-103
[5]   AN INTEGRATED MATHEMATICAL-MODEL OF THE DYNAMICS OF BLOOD-GLUCOSE AND ITS HORMONAL-CONTROL [J].
COBELLI, C ;
FEDERSPIL, G ;
PACINI, G ;
SALVAN, A ;
SCANDELLARI, C .
MATHEMATICAL BIOSCIENCES, 1982, 58 (01) :27-60
[6]  
COBELLI C, 1981, CARBOHYDRATE METABOL
[7]   INFLUENCE OF HYPERINSULINEMIA, HYPERGLYCEMIA, AND ROUTE OF GLUCOSE ADMINISTRATION ON SPLANCHNIC GLUCOSE EXCHANGE [J].
DEFRONZO, RA ;
FERRANNINI, E ;
HENDLER, R ;
WAHREN, J ;
FELIG, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (10) :5173-5177
[8]   GLUCOSE-ALANINE CYCLE [J].
FELIG, P .
METABOLISM-CLINICAL AND EXPERIMENTAL, 1973, 22 (02) :179-207
[9]   INFLUENCE OF ORAL GLUCOSE INGESTION ON SPLANCHNIC GLUCOSE AND GLUCONEOGENIC SUBSTRATE METABOLISM IN MAN [J].
FELIG, P ;
WAHREN, J ;
HENDLER, R .
DIABETES, 1975, 24 (05) :468-475
[10]   ROLE OF FRACTIONAL GLUCOSE EXTRACTION IN THE REGULATION OF SPLANCHNIC GLUCOSE-METABOLISM IN NORMAL AND DIABETIC MAN [J].
FERRANNINI, E ;
WAHREN, J ;
FELIG, P ;
DEFRONZO, RA .
METABOLISM-CLINICAL AND EXPERIMENTAL, 1980, 29 (01) :28-35
12