Combined membranous nephropathy and crescentic glomerulonephritis with concurrent anti-glomerular basement membrane antibody and myeloperoxidase-specific anti-neutrophil cytoplasmic antibody

被引：0

作者：

Iwafuchi, Yoichi ^{[1
]}

Morita, Takashi ^{[2
]}

Oyama, Yuko ^{[1
]}

Kamimura, Akira ^{[1
]}

Miyazaki, Shigeru ^{[3
]}

Narita, Ichiei ^{[4
]}

机构：

[1] Koseiren Sanjo Gen Hosp, Dept Internal Med, 5-1-62 Tsukanome, Sanjo 9550055, Japan

[2] Shinrakuen Hosp, Dept Pathol, Nishi Ku, 3-3-11 Shindoriminami, Niigata 9502087, Japan

[3] Shinrakuen Hosp, Kidney Ctr, Dept Internal Med, Nishi Ku, Niigata 9502087, Japan

[4] Niigata Univ, Grad Sch Med & Dent Sci, Dept Med 2, Clin Nephrol & Rheumatol,Chuo Ku, Niigata 9518510, Japan

来源：

CEN CASE REPORTS | 2013年 / 2卷 / 01期

关键词：

Membranous nephropathy; Crescentic glomerulonephritis; Anti-glomerular basement membrane antibody; Myeloperoxidase-specific anti-neutrophil cytoplasmic antibody;

D O I：

10.1007/s13730-012-0054-x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of a 71-year-old man with rapidly progressive nephritic syndrome and dual positivity for anti-glomerular basement membrane antibody and myeloperoxidase-specific anti-neutrophil cytoplasmic antibody. Renal biopsy revealed crescentic, mainly cellular, glomerulonephritis with granulomatous lesions, and advanced membranous changes. Membranous nephropathy had apparently existed for an extended period before the development of crescentic glomerulonephritis. In some studies reporting the simultaneous occurrence of both diseases, membranous nephropathy might be followed by crescentic glomerulonephritis, presumably from a histological point of view. Although we cannot prove a causal relationship between the two diseases, we caution that precise observations, especially histological, are necessary in similar cases.

引用

页码：107 / 111

页数：5

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