A patient with chronic, acquired, demyelinating, pure or predominantly motor asymmetric neuropathy is described. Electrophysiological tests showed multifocal conduction block in motor nerves. The sensory system was intact and the first signs of slight trival involvement appeared after 4 years of disease duration. The antiganglioside antibodies were present in serum and the patient responded to immunosuppressive therapy (azathioprine). Distinction of such cases from motor neuron disease is critical since motor demyelinating neuropathy is treatable in most cases.
机构:
Kansai Elect Power Hosp, Dept Neurol, Osaka, Japan
Kansai Elect Power Med Res Inst, Div Clin Neurol, Kobe, Hyogo, Japan
Kitano Hosp, Tazuke Kofukai Med Res Inst, Dept Neurol, Osaka, JapanKansai Elect Power Hosp, Dept Neurol, Osaka, Japan
Oka, Yuwa
Tsukita, Kazuto
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Kansai Elect Power Hosp, Dept Neurol, Osaka, Japan
Kyoto Univ, Grad Sch Med, Dept Neurol, Kyoto, Japan
Osaka Univ, Grad Sch Frontier Biosci, Lab Barriol & Cell Biol, Suita, Osaka, JapanKansai Elect Power Hosp, Dept Neurol, Osaka, Japan
Tsukita, Kazuto
Tsuzaki, Koji
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Kansai Elect Power Hosp, Dept Neurol, Osaka, Japan
Kansai Elect Power Med Res Inst, Div Clin Neurol, Kobe, Hyogo, JapanKansai Elect Power Hosp, Dept Neurol, Osaka, Japan
Tsuzaki, Koji
Takamatsu, Naoko
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Kansai Elect Power Hosp, Dept Neurol, Osaka, Japan
Tokushima Univ, Dept Neurol, Tokushima, JapanKansai Elect Power Hosp, Dept Neurol, Osaka, Japan
Takamatsu, Naoko
Hamano, Toshiaki
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Kansai Elect Power Hosp, Dept Neurol, Osaka, Japan
Kansai Elect Power Med Res Inst, Div Clin Neurol, Kobe, Hyogo, JapanKansai Elect Power Hosp, Dept Neurol, Osaka, Japan