ADRENALECTOMY CAUSES A DELAYED INCREASE OF INACTIVE PLASMA-RENIN IN RATS

被引：2

作者：

NIELSEN, AH ^{[1
]}

JOHANNESSEN, A ^{[1
]}

POULSEN, K ^{[1
]}

机构：

[1] ROYAL VET & AGR UNIV,INST ANAT & PHYSIOL,13 BULOWSVEJ,DK-1870 FREDERIKSBERG C,DENMARK

来源：

JOURNAL OF HYPERTENSION | 1991年 / 9卷 / 03期

关键词：

ADRENALECTOMY; ANGIOTENSINOGEN; INACTIVE RENIN; RENIN;

D O I：

10.1097/00004872-199103000-00007

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Using a new assay for inactive renin in rat plasma, inactive renin was unchanged 24 h after bilateral adrenalectomy but increased about threefold, from 0.43 Goldblatt units (GU)/I (range 0.27-0.62 GU/I; n = 14) to 1.24 GU/I (0.74-1.94 GU/I; n = 14) after 48 h. The increase was abolished by substitution with the mineralocorticoid deoxycorticosterone acetate. The results are in accordance with the high plasma concentration of inactive renin, previously reported in humans with adrenal insufficiency, and do not support activation of inactive renin in the circulation.

引用

页码：239 / 240

页数：2

共 50 条

[31] THE BASAL LEVELS OF ACTIVE AND INACTIVE PLASMA-RENIN CONCENTRATION IN INFANCY AND CHILDHOOD
FISELIER, T
DERKX, F
MONNENS, L
VANMUNSTER, P
PEER, P
SCHALEKAMP, M
CLINICAL SCIENCE, 1984, 67 (04) : 383 - 387
[32] PLASMA-RENIN
GIESE, J
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1972, 29 : 74 - &
[33] CONTROL PLASMA-RENIN ACTIVITY AND CHANGES IN SYMPATHETIC TONE AS DETERMINANTS OF MINOXIDIL-INDUCED INCREASE IN PLASMA-RENIN ACTIVITY
OMALLEY, K
VELASCO, M
WELLS, J
MCNAY, JL
JOURNAL OF CLINICAL INVESTIGATION, 1975, 55 (02): : 230 - 235
[34] RESPONSE OF PLASMA-IMMUNOREACTIVE ACTIVE RENIN, INACTIVE RENIN, PLASMA-RENIN ACTIVITY, AND ALDOSTERONE TO HEMODIALYSIS IN PATIENTS WITH DIABETIC NEPHROPATHY
SASAMURA, H
SUZUKI, H
TAKITA, T
HAYASHI, M
OHNO, J
SHIRAI, T
SARUTA, T
CLINICAL NEPHROLOGY, 1990, 33 (06) : 288 - 292
[35] REDUCED INCREASE IN PLASMA-RENIN ACTIVITY ON WATER-DEPRIVATION IN BLIND HEREDITARY MICROPHTHALMIC RATS
NAGAI, K
STOYNEV, AG
NAGAI, N
NAKAGAWA, H
NEUROSCIENCE LETTERS, 1993, 149 (02) : 217 - 220
[36] COMPARATIVE-STUDY OF ACTIVE AND INACTIVE PLASMA-RENIN IN HEALTHY INFANTS AND ADULTS
VANACKER, KJ
SCHARPE, SL
LYNEN, PJ
AMERY, AK
JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY, 1983, 21 (12): : 775 - 778
[37] DIURNAL RHYTHM OF PLASMA-RENIN ACTIVITY (PRA) IN RATS
SARGENT, C
CANGIANO, JL
MARTINEZMALDONADO, M
CLINICAL RESEARCH, 1977, 25 (03): : A301 - A301
[38] POSSIBLE DETERMINANTS OF PLASMA-RENIN ACTIVITY IN INFANT RATS
SOLOMON, S
IAINA, A
ELIAHOU, H
PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, 1976, 153 (02): : 309 - 313
[39] EFFECTS OF PSYCHOSOCIAL STIMULI ON PLASMA-RENIN ACTIVITY IN RATS
CLAMAGE, DM
SANFORD, CS
VANDER, AJ
MOUW, DR
AMERICAN JOURNAL OF PHYSIOLOGY, 1976, 231 (04): : 1290 - 1294
[40] EFFECT OF PSYCHOSOCIAL STRESS ON PLASMA-RENIN ACTIVITY IN RATS
CLAMAGE, D
SANFORD, C
VANDER, A
MOUW, D
CLINICAL RESEARCH, 1976, 24 (04): : A603 - A603

← 1 2 3 4 5 →