Microwave assisted synthesis of novel thiazolidinone analogues as possible bioactive agents

被引：16

作者：

Adhikari, Adithya ^{[1
]}

Kalluraya, Balakrishna ^{[1
]}

Sujith, Kizhakke Veedu ^{[1
]}

Gouthamchandra, Kuluvar ^{[2
]}

Mahmood, Riaz ^{[2
]}

机构：

[1] Mangalore Univ, Dept Studies Chem, Mangalagangothri 574199, Karnataka, India

[2] Jnanasahyadri Kuvempu Univ, Dept PG Studies & Res Biotechnol & Bioinformat, Shankaraghatta 577451, Karnataka, India

来源：

JOURNAL OF ADVANCED RESEARCH | 2012年 / 3卷 / 04期

关键词：

4-Thiazolidinone; Solvent free reaction; Microwave assisted synthesis; Antioxidant; Antibacterial; Antifungal activity;

D O I：

10.1016/j.jare.2011.10.003

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A series of 5-{[(6-substituted-2-hydroxyquinolin-3-yl) methylidene]/5-[(7-substitutedtet-razolo[1,5-a] quinoline-4-yl) methylidene]}-2-[(4-substitutedphenyl) amino]-1,3-thiazol-4(5H)-one was successfully synthesized under solvent free conditions by microwave irradiation in high yield. Structures of these newly synthesized compounds were established on the basis of spectral and analytical data. These novel compounds were also evaluated for their in vitro antioxidant, antibacterial and antifungal activity. (C) 2011 Cairo University. Production and hosting by Elsevier B.V. All rights reserved.

引用

页码：325 / 330

页数：6

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