AIRWAY EPITHELIUM-DERIVED INHIBITORY FACTOR

被引:76
作者
GOLDIE, RG
FERNANDES, LB
FARMER, SG
HAY, DWP
机构
[1] NOVA PHARMACEUT CORP,BALTIMORE,MD 21224
[2] SMITHKLINE BEECHAM LABS,DEPT PHARMACOL,KING OF PRUSSIA,PA 19406
关键词
D O I
10.1016/0165-6147(90)90320-8
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Various bronchoactive agents can induce the release from the airway epithelium of an inhibitory substance that is able to relax certain tissues including rat aorta and possibly also airway smooth muscle. This substance, whose existence has recently been confirmed using a new bioassay system, is distinct from nitric oxide (EDRF) and is also known to be non-prostanoid in nature. Roy Goldie and colleagues describe the properties of this factor, and its potential clinical significance. © 1990.
引用
收藏
页码:67 / 70
页数:4
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