EFFECTS OF CHICKEN EGG-WHITE ON THE PROLIFERATION AND NEURITE OUTGROWTH OF MAMMALIAN-CELLS

被引：5

作者：

ZOU, C ^{[1
]}

KOBAYASHI, K ^{[1
]}

KATO, A ^{[1
]}

机构：

[1] YAMAGUCHI UNIV,DEPT BIOCHEM,YAMAGUCHI 753,JAPAN

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1991年 / 39卷 / 12期

关键词：

D O I：

10.1021/jf00012a007

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

The growth-promoting and neurite-growth-promoting effects of chicken egg white on mammalian cell were studied by using CV-1, BHK-21, IEC-18, and PC12 cell lines. Chicken egg white promoted the proliferation of CV-1, BHK-21, and IEC-18 cell fines. The growth-promoting activity of egg white was dose dependent and seeding cell density dependent. Although chicken egg white did not exhibit cell-growth-promoting activity as strong as that of serum, it promoted the cell growth in cooperation with serum. In addition to growth-promoting activity, egg white exhibited a strong activity to induce the process growth of CV-1 cells. During the 12-h cell culture, about half of the CV-1-cells having long processes grew in the egg white supplemented medium. Further evidence of the existence of a process outgrowth-promoting component in egg white was obtained by using the PC12 cell line, which extends neurites in response to nerve growth factor.

引用

页码：2137 / 2141

页数：5

共 9 条

[1] PRESENCE OF CELL-GROWTH PROMOTING PEPTIDES IN CHICKEN EGG-WHITE EXTRACT [J].