CLONING AND SEQUENCE-ANALYSIS OF THE CORYNEBACTERIUM-DIPHTHERIAE DTXR HOMOLOG FROM STREPTOMYCES-LIVIDANS AND S-PILOSUS ENCODING A PUTATIVE IRON REPRESSOR PROTEIN

被引：42

作者：

GUNTERSEEBOTH, K

SCHUPP, T

机构：

[1] CIBA GEIGY AG,ANIM HLTH BIOTECHNOL,CH-4002 BASEL,SWITZERLAND

[2] CIBA GEIGY AG,PHARMA RES CDDT,CH-4002 BASEL,SWITZERLAND

来源：

GENE | 1995年 / 166卷 / 01期

关键词：

IRON REGULATION; DESFERRIOXAMINE; SIDEROPHORE;

D O I：

10.1016/0378-1119(95)00628-7

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The iron-regulated promoter involved in desferrioxamine B synthesis of Streptomyces pilosus contains a region homologous to the iron repressor (DtxR)-binding site of the diphtheria toxin gene promoter in Corynebacterium diphtheriae [Gunter et al., J. Bacteriol. 175 (1993) 3295-3302]. Here, we report the cloning and sequencing of the putative Streptomyces iron repressor gene, homologous to dtxR of C. diphtheriae. The N-terminal 139 amino acids of the deduced protein are 73% identical to DtxR.

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页码：117 / 119

页数：3

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