THE T-GENES IN EMBRYOGENESIS

被引：188
作者：
HERRMANN, BG
KISPERT, A
机构：
来源：
TRENDS IN GENETICS | 1994年 / 10卷 / 08期
关键词：
D O I：
10.1016/0168-9525(90)90011-T
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Since its identification in 1927, the mouse T (Brachyury) locus has been implicated in mesoderm formation and and notochord differentiation Recent work; has demonstrated that this gene encodes a putative transcription factor expressed specifically in nascent mesoderm and in the differentiating notochord. Homologous genes have been cloned from the frog Xenopus laevis, the zebrafish Brachydanio rerio and the ascidian Halocynthia roretzi. The T gene is an important tool for elucidating mesodermal and embryonic pattern formation.
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页码：280 / 286
页数：7
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