Spindle cell carcinoma of the tongue: a rare variant of squamous cell carcinoma

被引：13

作者：

Biradar, Manisha V. ^{[1
]}

Dantkale, Sunita S. ^{[1
]}

Abhange, Rahul S. ^{[1
]}

Kamra, Hemlata T. ^{[1
]}

Birla, Khushboo ^{[1
]}

机构：

[1] Govt Med Coll, Dept Pathol, Latur 413512, India

来源：

ECANCERMEDICALSCIENCE | 2014年 / 8卷

关键词：

biphasic; epithelial; mesenchymal; spindle cell; squamous;

D O I：

10.3332/ecancer.2014.447

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Spindle cell carcinoma (SpCC), a rare, aggressive variant of squamous cell carcinoma (SCC), is characterised by proliferation of epithelial and mesenchymal components. It is important to diagnose this variant of SCC, because of its tendency to recur and early metastasis. It accounts for 1% of all tumours in the oral cavity. In this paper, we have reported a case of SpCC of the tongue in a 65-year-old male who presented with a polypoidal growth over the lateral border of his tongue with a short history of one month. Immunohistochemical expression of cytokeratin was strongly positive in the epithelial component and focally in the spindle cell component. The spindle cell component showed a strong positivity for vimentin.

引用

页数：7

共 12 条

[1]

Chen YKLC., 1998, ORAL MED PATHOL, V3, P51

[2] Spindle cell carcinoma of head and neck: an immunohistochemical and molecular approach to its pathogenesis [J].