CYTOKINES

被引:29
作者
HOLTMANN, H
RESCH, K
机构
[1] Medizinische Hochschule Hannover, Institut für Klinische Molekularpharmakologie, Hannover
关键词
D O I
10.1007/BF01143192
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The defense of the organism against pathogens involves complex processes in which many different types of cells take part. Their functions are coordinated by polypeptide mediators collectively named cytokines. The intense research devoted to these molecules in the past has yielded an insight into their molecular characteristics, mode of action, physiological function, and their deleterious role in numerous diseases. Yet therapeutic application of that knowledge - either controlled administration of cytokines or neutralization of their negative effects in certain pathological processes - despite initial achievements has remained a major challenge.
引用
收藏
页码:178 / 187
页数:10
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