PROGNOSTIC VALUE OF SONOGRAPHY IN CHILDHOOD NEPHROTIC SYNDROME

被引:8
|
作者
GERSHEN, RS [1 ]
BRODY, AS [1 ]
DUFFY, LC [1 ]
SPRINGATE, JE [1 ]
机构
[1] SUNY BUFFALO,DEPT PEDIAT,BUFFALO,NY 14222
关键词
NEPHROTIC SYNDROME; KIDNEY ULTRASOUND; ECHOGENIC KIDNEYS; NEPHROMEGALY;
D O I
10.1007/BF00868271
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
This retrospective case review of 43 children with primary nephrotic syndrome was designed to evaluate the relationship among renal ultrasound findings at presentation, subsequent corticosteroid responsiveness and histological diagnoses. Fifty-one percent of patients had abnormal sonograms; nephromegaly was present in 42% and increased renal echogenicity in 35%. There was no relationship between nephromegaly and either response to corticosteroids or specific glomerular lesions causing nephrosis. Although the presence of echogenic kidneys did not denote a particular type of renal disease, it was significantly more frequent in corticosteroid-resistant than in corticosteroid-responsive patients (62% vs. 18%, P <0.05). We conclude that increased renal echogenicity at time of presentation is a possible indicator of corticosteroid resistance in children with primary nephrotic syndrome.
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页码:76 / 78
页数:3
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