FLOW CYTOMETRIC DNA HISTOGRAMS OF PARAFFIN-EMBEDDED PHEOCHROMOCYTOMAS

被引：5
|
作者：
HOSAKA, Y
ASO, Y
RAINWATER, LM
GRANT, CS
FARROW, GM
VANHEERDEN, JA
LIEBER, MM
机构：
来源：
UROLOGIA INTERNATIONALIS | 1991年 / 47卷
关键词：
PHEOCHROMOCYTOMA; FLOW CYTOMETRY; DNA HISTOGRAM; PARAFFIN-EMBEDDED SPECIMEN;
D O I：
10.1159/000282264
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
We proposed a new classification of pheochromocytomas according to DNA ploidy patterns. Proliferation index (PI = S% + 4C%) might be an alternative to 4C% which was used as a critical marker of DNA nonaneuploid histograms. The follow-up survey revealed that DNA tetraploid with minimum increase of PI could not rule out the substantial possibility of malignancy and the comparison of DNA diploid histograms disclosed that 22 and 0% showed significant increase of the ratio of 4C% to S% under PI and 4C% criteria, respectively. In conclusion, 4C% was more effective and reliable than PI in order to classify DNA nonaneuploid pheochromocytomas.
引用
收藏
页码：100 / 103
页数：4
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