IDENTIFICATION OF A NUCLEAR RETINOIC ACID-BINDING ACTIVITY REPRESENTATIVE OF ENDOGENEOUS RETINOIC ACID RECEPTORS IN THE NUCLEI OF RAT-LIVER AND TESTIS

被引：1
|
作者：
MANO, H [1 ]
KUMAKURA, C [1 ]
KITAMURA, A [1 ]
MORINO, H [1 ]
KATO, S [1 ]
MASUSHIGE, S [1 ]
机构：
[1] TOKYO UNIV AGR, FAC AGR, DEPT AGR CHEM, SETAGAYA KU, TOKYO 156, JAPAN
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1993年 / 57卷 / 08期
关键词：
D O I：
10.1271/bbb.57.1400
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We found a nuclear RA-binding activity by using a sucrose-density-gradient assay from rat liver and testis. From the sedimentation analysis, and the comparison with cloned RARs, it is likely that these binding activities represent endogenous RARs. Furthermore we showed that these binding activities were constant irrespective of the retinoid status in the rat.
引用
收藏
页码：1400 / 1402
页数：3
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