INHIBITION OF BIOLUMINESCENCE IN A RECOMBINANT ESCHERICHIA-COLI

被引：4

作者：

RYCHERT, R

MORTIMER, M

机构：

[1] Department of Biology, Boise State University, Boise, Idaho

来源：

ENVIRONMENTAL TOXICOLOGY AND WATER QUALITY | 1991年 / 6卷 / 04期

关键词：

D O I：

10.1002/tox.2530060406

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Six toxicants were evaluated for their ability to inhibit bioluminescence in a recombinant Escherichia coli harboring pJE202 that contained the lux (light-producing) genes. With the recombinant E. coli the rank order for toxicity was Zn2+ > ethidium bromide > sodium pentachlorophenate > Cu2+ > 2,4-dichlorophenoxyacetic acid. The light-producting recombinant E. coli was insensitive to sodium dodecyl sulfate, and was much less sensitive than the Microtox test with the six toxicants. These results do not preclude the use of recombinant bacteria in toxicity testing.

引用

页码：415 / 421

页数：7

共 22 条

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