INCREASED SERUM LEVEL OF INTERLEUKIN-5 IN A PATIENT WITH EPISODIC ANGIOEDEMA AND EOSINOPHILIA SYNDROME

被引：12

作者：

MURAKAMI, T

KATO, J

KOGAWA, K

WATANABE, N

SAKAMAKI, S

KOHGO, Y

HAMABE, K

ISHIYAMA, N

ENOKIHARA, H

NIITSU, Y

机构：

[1] Department of Internal Medicine (Section 4), Sapporo Medical College, Sapporo

[2] Sapporo Social Benefit General Hospital, Sapporo

[3] Third Department of Internal Medicine, Dokkyou University School of Medicine, Mibu

来源：

INTERNAL MEDICINE | 1993年 / 32卷 / 04期

关键词：

EPISODIC ANGIOEDEMA AND EOSINOPHILIA SYNDROME; CYTOKINES; CORTICOSTEROID TREATMENT;

D O I：

10.2169/internalmedicine.32.343

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A case of episodic angioedema and eosinophilia syndrome is reported. An 18-year-old male suffered from monthly episodes of angioedema, pruritic papules, weight gain, and fever for twelve years. During the episodes, peripheral eosinophils and serum levels of interleukin (IL)-5, an eosinophil proliferating cytokine were elevated. Extensive evaluations disclosed neither visceral involvement nor evidence of parasitic infections, collagen diseases, or neoplastic disorders. Corticosteroid treatment brought about a dramatic clinical improvement concomitant with decrement of eosinophils and serum IL-5 was observed. These observations suggest that IL-5 may be a causative factor for this pathological state.

引用

页码：343 / 345

页数：3

共 15 条

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