ASYMMETRIC-SYNTHESIS OF SULFINIMINES - APPLICATIONS TO THE SYNTHESIS OF NONRACEMIC BETA-AMINO-ACIDS AND ALPHA-HYDROXYL-BETA-AMINO-ACIDS

被引：149

作者：

DAVIS, FA

REDDY, RT

REDDY, RE

机构：

[1] Department of Chemistry, Drexel University, Philadelphia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 24期

关键词：

D O I：

10.1021/jo00050a007

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Asymmetric oxidation of sulfenimines 1 affords sulfinimines 2 (88-90% ee) which are chiral ammonia imine synthons useful in the enantioselective synthesis of beta-amino acids and alpha-hydroxy-beta-amino acids such as the C-13 side chain of taxol (2R,3S)-7.

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页码：6387 / 6389

页数：3

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