ORAL AND PHARYNGEAL ADENOSQUAMOUS CARCINOMA - A REPORT OF 4 CASES WITH IMMUNOHISTOCHEMICAL STUDIES

被引:0
作者
MARTINEZMADRIGAL, F [1 ]
BADEN, E [1 ]
CASIRAGHI, O [1 ]
MICHEAU, C [1 ]
机构
[1] UNIV MED & DENT NEW JERSEY,NEW BRUNSWICK,NJ 08903
关键词
ADENOSQUAMOUS CARCINOMA; ORAL AND PHARYNGEAL TUMORS; IMMUNOHISTOCHEMISTRY;
D O I
暂无
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Four cases of adenosquamous carcinoma from the oral and pharyngeal cavities were analyzed by light microscopy and immunohistochemistry. Lymph node metastases were present in three cases. One patient died 2 years after treatment. All four carcinomas presented a mixture of squamous and glandular mucus-secreting neoplastic elements. Immunostaining for high-molecular-weight cytokeratins (KL1) was constantly positive in both squamous and glandular tumor cells. Antibodies against low-molecular-weight cytokeratins (K19) and carcinoembryonic antigen were positive only in the glandular component. The histological aspect and the immunohistochemical phenotype of these tumors is similar to the ordinary squamous cell carcinoma and adenocarcinoma, respectively.
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页码:255 / 258
页数:4
相关论文
共 16 条
[1]  
BOSWELL JT, 1965, CANCER, V18, P181, DOI 10.1002/1097-0142(196502)18:2<181::AID-CNCR2820180209>3.0.CO
[2]  
2-3
[3]  
GERUGHTY RM, 1968, CANCER, V22, P1140, DOI 10.1002/1097-0142(196811)22:6<1140::AID-CNCR2820220610>3.0.CO
[4]  
2-1
[5]  
HEALEY WV, 1970, CANCER, V26, P368, DOI 10.1002/1097-0142(197008)26:2<368::AID-CNCR2820260219>3.0.CO
[6]  
2-K
[7]  
HYAMS VJ, 1988, ATLAS TUMOR PATHOL, V25, P85
[8]   ADENOID SQUAMOUS-CELL CARCINOMA (ADENOACANTHOMA) OF ORAL LABIAL MUCOSA - CLINICOPATHOLOGIC STUDY OF 15 CASES [J].
JACOWAY, JR ;
NELSON, JF ;
BOYERS, RC .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 1971, 32 (03) :444-+
[9]   THE CATALOG OF HUMAN CYTOKERATINS - PATTERNS OF EXPRESSION IN NORMAL EPITHELIA, TUMORS AND CULTURED-CELLS [J].
MOLL, R ;
FRANKE, WW ;
SCHILLER, DL ;
GEIGER, B ;
KREPLER, R .
CELL, 1982, 31 (01) :11-24
[10]  
PEEL RL, 1985, SURG PATHOLOGY HEAD, P607