(3R,4S,5S)-5-BENZYL-4-HYDROXY-3-[1(S)-(1,1-DIMETHYLETHOXYCARBONYLAMINO)-2-PHENYL-ETHYL]PYRROLIDIN-2-ONE

被引：0
作者：
WEBER, HP [1 ]
ETTMAYER, P [1 ]
HUBNER, M [1 ]
GSTACH, H [1 ]
机构：
[1] SANDOZ GMBH,FORSCHUNGSINST,A-1235 VIENNA,AUSTRIA
来源：
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1995年 / 51卷
关键词：
D O I：
10.1107/S010827019500504X
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The title compound, tert-butyl {1(S)-[(3R,4S,5S)-5-benzyl-4-hydroxy-2-oxo-3 -pyrrolidinyl]-2-phenylethyl}carbamate, C24H30N2O4, is an example of an all-cis trisubstituted pyrrolidin-2-one. The absolute configurations of the C atoms in the lactam ring were assigned to be 3R, 4S and 5S relative to the known chirality, 1S, of the C-alpha atom of the L-phenylalanine fragment in the compound. There is one intramolecular hydrogen bond between the pyrrolidin-2-one carbonyl O atom and the N-H group of the L-phenylalanine fragment [N-H ... O 2.936(5) Angstrom].
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页码：2139 / 2141
页数：3
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