(3R,4S,5S)-5-BENZYL-4-HYDROXY-3-[1(S)-(1,1-DIMETHYLETHOXYCARBONYLAMINO)-2-PHENYL-ETHYL]PYRROLIDIN-2-ONE

被引：0

作者：

WEBER, HP ^{[1
]}

ETTMAYER, P ^{[1
]}

HUBNER, M ^{[1
]}

GSTACH, H ^{[1
]}

机构：

[1] SANDOZ GMBH,FORSCHUNGSINST,A-1235 VIENNA,AUSTRIA

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1995年 / 51卷

关键词：

D O I：

10.1107/S010827019500504X

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The title compound, tert-butyl {1(S)-[(3R,4S,5S)-5-benzyl-4-hydroxy-2-oxo-3 -pyrrolidinyl]-2-phenylethyl}carbamate, C24H30N2O4, is an example of an all-cis trisubstituted pyrrolidin-2-one. The absolute configurations of the C atoms in the lactam ring were assigned to be 3R, 4S and 5S relative to the known chirality, 1S, of the C-alpha atom of the L-phenylalanine fragment in the compound. There is one intramolecular hydrogen bond between the pyrrolidin-2-one carbonyl O atom and the N-H group of the L-phenylalanine fragment [N-H ... O 2.936(5) Angstrom].

引用

页码：2139 / 2141

页数：3

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