COMPARATIVE-ANALYSIS OF COMPUTED TOMOGRAPHIC AND MAGNETIC-RESONANCE-IMAGING SCANS IN ALZHEIMER PATIENTS AND CONTROLS

被引:33
作者
SANDOR, T
JOLESZ, F
TIEMAN, J
KIKINIS, R
JONES, K
ALBERT, M
机构
[1] BRANDEIS UNIV, HELLER SCH, WALTHAM, MA 02254 USA
[2] MASSACHUSETTS GEN HOSP, DEPT PSYCHIAT, BOSTON, MA 02114 USA
[3] MASSACHUSETTS GEN HOSP, DEPT NEUROL, BOSTON, MA 02114 USA
[4] HARVARD UNIV, SCH MED, BOSTON, MA 02115 USA
关键词
D O I
10.1001/archneur.1992.00530280069024
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Ten patients with Alzheimer's disease underwent computed tomography and magnetic resonance imaging at the same point in time. The mean Mini-Mental State examination score of the patients was 23, indicating that they were mildly impaired. Ten age-equivalent controls also obtained computed tomographic and magnetic resonance imaging scans. A semiautomated computer program analyzed nine comparable regions of interest on each set of scans. When regions of interest from both types of scans were combined in the same discriminant function analysis, the first two variables selected were from the magnetic resonance imaging data set, and they significantly differentiated 95% of the patients and controls.
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页码:381 / 384
页数:4
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