AUTORADIOGRAPHIC ASSESSMENT OF PINEAL-GLAND GLUCOSE-UTILIZATION AND CAPILLARY-PERMEABILITY IN THE UNANESTHETIZED RAT

被引：4

作者：

CICCIARELLO, R

DAVELLA, D

DEBLASI, F

PRINCI, P

RUSSO, F

PALAZZOLO, A

CANALE, F

ALBIERO, F

MESITI, M

GERMANO, A

PENSABENE, V

SCANARINI, M

机构：

[1] UNIV MESSINA, FAC MED, INST ONCOL, I-98100 MESSINA, ITALY

[2] UNIV MESSINA, FAC PHARM, CTR DRUG INFORMAT, I-98100 MESSINA, ITALY

[3] UNIV MESSINA, FAC MED, NEUROSURG CLIN, I-98100 MESSINA, ITALY

[4] CALABRIA CITY HOSP, USL 31, REGGIO DI CALALBRIA, ITALY

[5] UNIV HOSP PADOVA, DIV NEUROSURG, PADUA, ITALY

来源：

CHILDS NERVOUS SYSTEM | 1990年 / 6卷 / 04期

关键词：

Capillary permeability; Glucose metabolism; Pineal gland; Positron emission tomography; Quantitative autoradiography;

D O I：

10.1007/BF01850978

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Pineal gland glucose utilization (GU) and capillary permeability (CP) were measured in unanesthetized rats, using complementary quantitative autoradiographic techniques. GU values within the pineal tissue were homogeneously distributed around 70 μmol of glucose/100 g each min, i.e., they were approximately 30% lower than in the cortical gray structures. The blood-to-brain transfer constant of [14C]-α-aminoisobutyric acid, as an index of CP, was up to ten orders of magnitude higher than that for the rest of the brain. These measurements were carried out at that point in the circadian rhythm that corresponds to the minimum level of neurosecretory activity of the pineal gland. © 1990 Springer-Verlag.

引用

页码：222 / 224

页数：3

共 8 条

[1] TRANSPORT OF ALPHA-AMINOISOBUTYRIC-ACID ACROSS BRAIN CAPILLARY AND CELLULAR MEMBRANES [J].