SYNTHESIS IN ISOQUINOLINE SERIES . SYNTHESIS AND CHEMICAL TRANSFORMATION OF 2,3-DIHYDRO-4(1H)-ISOQUINOLONES

被引：40

作者：

GRETHE, G

LEE, HL

USKOKOVI.M

BROSSI, A

机构：

[1] Chemical Research Department, Hoffmann-La Roche, Inc., Nutley

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1968年 / 33卷 / 02期

关键词：

D O I：

10.1021/jo01266a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several 2,3-dihydro-4(1H)-isoquinolones have been prepared by Dieckmann cyclization of suitable N-(o-carbalkoxybenzyl)glycine ester derivatives followed by hydrolysis and decarboxylation of the intermediate β-keto esters. The importance of these compounds as useful intermediatesis shown by their conversion into various isoquinoline derivatives. © 1968, American Chemical Society. All rights reserved.

引用

页码：494 / &

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