NARCICLASINE-4-O-BETA-D-GLUCOPYRANOSIDE, A GLUCOSYLOXY AMIDIC PHENANTHRIDONE DERIVATIVE FROM PANCRATIUM-MARITIMUM

被引：32

作者：

ABOUDONIA, AH

DEGIULIO, A

EVIDENTE, A

GABER, M

HABIB, AA

LANZETTA, R

ELDIN, AAS

机构：

[1] CNR,IST CHIM MOLEC INTERESSE BIOL,I-80072 ARCO,ITALY

[2] UNIV NAPOLI FREDERICO 2,DIPARTIMENTO CHIM ORGAN & BIOL,I-80134 NAPLES,ITALY

[3] UNIV NAPOLI FREDERICO 2,DIPARTIMENTO SCI CHIM AGR,I-80055 PORTICI,ITALY

来源：

PHYTOCHEMISTRY | 1991年 / 30卷 / 10期

关键词：

PANCRATIUM-MARITIMUM; AMARYLLIDACEAE; BULBS; ALKALOIDS; NARCICLASINE; GLUCOSYLOXY ALKALOIDS; NARCICLASINE-4-O-BETA-D-GLUCOPYRANOSIDE;

D O I：

10.1016/0031-9422(91)83226-B

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bulbs of Pancratium maritimum were found to contain a new glucosyloxy phenolic metabolite as well as 14 known Amaryllidaceae alkaloids. The structure of the phenolic metabolite was elucidated by spectroscopic and chemical methods, and it was identified as narciclasine-4-O-beta-D-glucopyranoside. When tested in Artemia salina and potato disc assays the new glucoside showed cytotoxic and antitumour activity very similar to narciclasine.

引用

页码：3445 / 3448

页数：4

共 16 条

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ABOUDONIA AH, 1991, UNPUB PLANTA MED

[2]

AHMED ZF, 1964, LLOYD, V27, P115

[3]

Ali A. A., 1984, B PHARM SCI, V7, P351

[4]

[Anonymous], 1971, PROBIT ANAL