ROLLINONE, A REVISION AND EXTENSION OF STRUCTURE

被引：10

作者：

ABREO, MJ ^{[1
]}

SNEDEN, AT ^{[1
]}

机构：

[1] VIRGINIA COMMONWEALTH UNIV,DEPT CHEM,RICHMOND,VA 23284

来源：

JOURNAL OF NATURAL PRODUCTS | 1990年 / 53卷 / 04期

关键词：

D O I：

10.1021/np50070a034

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The structure of rollinone [2] has been revised according to recently acquired 2D-nmr data. Instead of the previously reported terminal γ-methylbutyrolactone and 14-keto moieties, rollinone [2] was found to contain a butyrolactone between C-1 and C-4 with a pendant acetylmethyl moiety at C-2. The relative stereochemistry between C-15 and C-24 in rollinone [2] was established as erythro-cis-threo-cis-threo (or threo-cis-threo-cis-erythro) by1H-nmr experiments using the diacetate derivative. The structure was confirmed via chemical conversion of 25-desoxy-4-hydroxyneorollinicin [1] into 2. © 1990, American Chemical Society. All rights reserved.

引用

页码：983 / 985

页数：3

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