METHIMAZOLE-INDUCED AGRANULOCYTOSIS PRECEDED BY TRANSIENT GRANULOCYTOPENIA - A CASE-REPORT

被引:0
作者
SCHUT, NH
WIERSINGA, WM
VANOERS, MH
机构
[1] UNIV AMSTERDAM,ACAD MED CTR,DEPT ENDOCRINOL,1105 AZ AMSTERDAM,NETHERLANDS
[2] UNIV AMSTERDAM,ACAD MED CTR,DEPT HAEMATOL,1105 AZ AMSTERDAM,NETHERLANDS
关键词
AGRANULOCYTOSIS; GRANULOCYTOPENIA; ANTITHYROID DRUGS; HYPERTHYROIDISM;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 36-year-old patient, euthyroid under methimazole treatment, was admitted because of an active Graves' ophthalmopathy and found to have a transient granulocytopenia. Forty-five days after this episode she developed classical agranulocytosis because of which the methimazole was stopped. The agranulocytosis occurred more than 20 months after the initiation of antithyroid drug therapy. Other causes for the initial phase of granulocytopenia were not found.
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页码:71 / 73
页数:3
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