AUTOENCAPSULATION THROUGH INTERMOLECULAR FORCES - A SYNTHETIC SELF-ASSEMBLING SPHERICAL COMPLEX

被引：206
作者：
MEISSNER, RS
REBEK, J
DEMENDOZA, J
机构：
[1] MIT, DEPT CHEM, CAMBRIDGE, MA 02139 USA
[2] UNIV AUTONOMA MADRID, DEPT QUIM, E-28049 MADRID, SPAIN
来源：
SCIENCE | 1995年 / 270卷 / 5241期
关键词：
D O I：
10.1126/science.270.5241.1485
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The synthesis and characterization of a system for the study of molecular recognition phenomena are described. The system involves a tetraurea molecule that is capable of assembly into various associated states through hydrogen bonding. In organic solvents, the dynamic transition between a low-ordered (aggregate) state and a highly ordered dimeric assembly can be induced by the introduction of smaller molecules of appropriate size and shape. These smaller molecules, such as benzene, adamantanes, and ferrocenes, act as guests that occupy the pseudospherical capsule formed by the dimeric host, Among various guests, those that best fill the cavity and offer chemical complementarity to the host are preferentially encapsulated.
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页码：1485 / 1488
页数：4
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