ASYMMETRIC-SYNTHESIS BY ENZYMATIC-HYDROLYSIS OF PROCHIRAL DIENOL DIACETATE

被引：8

作者：

DUHAMEL, P ^{[1
]}

RENOUF, P ^{[1
]}

CAHARD, D ^{[1
]}

YEBGA, A ^{[1
]}

POIRIER, JM ^{[1
]}

机构：

[1] INST RECH CHIM ORGAN FINE,F-76821 MONT ST AIGNAN,FRANCE

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 12期

关键词：

D O I：

10.1016/S0957-4166(00)82222-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Enzymatic hydrolysis of prochiral dienol diacetate 1 by Candida cylindracea lipase (C C L) leads to the keto enol acetate 2 in high yield with an enantiomeric excess > 98 %. The S configuration of the asymmetric center was assigned.

引用

页码：2447 / 2450

页数：4

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