STEREOSELECTIVE SYNTHESIS, CONFORMATION AND COMPLEXING BEHAVIOR OF 1,2,3-TRISUBSTITUTED CHIRAL FERROCENES

Sulfur and phosphorus substituents have been introduced into the 2 and 5 positions of the ferrocene nucleus in chiral 1-(N,N-dimethylamino)ethylferrocene by stereoselective lithiation and reaction with electrophiles. The conformations of the diastereoisomeric trisubstituted ferrocenes obtained have been determined by NMR methods. The compounds behave as bidentate or monodentate ligands for transition metals, leaving one or two coordination sites for a further metal. NMR experiments suggest different site selectivity in the formation of nickel(II) and rhodium(I) complexes. © 1990.