Oral Alendronate Treatment for Severe Polyostotic Fibrous Dysplasia due to McCune-Albright Syndrome in a Child: A Case Report

被引:6
作者
Andrade Aragao, Ana Luiza [1 ]
Silva, Ivani Novato [1 ]
机构
[1] Univ Fed Minas Gerais, Div Endocrinol Pediat, Dept Pediat, Hosp Clin,Fac Med, Ave Alfredo Balena,190,Sala 267, BR-30130100 Belo Horizonte, MG, Brazil
关键词
D O I
10.1155/2010/432060
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Polyostotic fibrous dysplasia (FD) associated to McCune-Albright Syndrome (MAS) often leads to fractures, deformities, and bone pain resulting in bad quality of life. Parenteral bisphosphonates have been used in children and adolescents to improve these symptoms with few adverse effects. We evaluated the response to oral Alendronate in a girl with severe MAS FD and observed improved quality of life with reduction of bone pain.
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共 30 条
[1]   Clinical Review: Bisphosphonate Use in Childhood Osteoporosis [J].
Bachrach, Laura K. ;
Ward, Leanne M. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2009, 94 (02) :400-409
[2]  
Bianchi ML, 2000, ARTHRITIS RHEUM-US, V43, P1960, DOI 10.1002/1529-0131(200009)43:9<1960::AID-ANR6>3.0.CO
[3]  
2-J
[4]   Pharmacovigilance study of alendronate in England [J].
Biswas, PN ;
Wilton, LV ;
Shakir, SAW .
OSTEOPOROSIS INTERNATIONAL, 2003, 14 (06) :507-514
[5]   McCune-Albright syndrome: a case report and review of the literature [J].
Bolger, WE ;
Ross, AT .
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2002, 65 (01) :69-74
[6]   Use of high-dose oral bisphosphonate therapy for symptomatic fibrous dysplasia of the skull [J].
Chao, Kevin ;
Katznelson, Laurence .
JOURNAL OF NEUROSURGERY, 2008, 109 (05) :889-892
[7]   Treatment of fibrous dysplasia of bone with intravenous pamidronate: long-term effectiveness and evaluation of predictors of response to treatment [J].
Chapurlat, RD ;
Hugueny, P ;
Delmas, PD ;
Meunier, PJ .
BONE, 2004, 35 (01) :235-242
[8]  
Defilippi C, 2006, J PEDIATR ENDOCR MET, V19, P561
[9]  
Diaz A, 2007, J PEDIATR ENDOCR MET, V20, P853
[10]   Fibrous dysplasia - Pathophysiology, evaluation, and treatment [J].
DiCaprio, MR ;
Enneking, WF .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 2005, 87A (08) :1848-1864