PHARMACOKINETIC AND BIO-PHARMACEUTIC PROFILE OF CHLORDIAZEPOXIDE HCL IN HEALTHY SUBJECTS - MULTIPLE-DOSE ORAL-ADMINISTRATION

被引：32

作者：

BOXENBAUM, HG ^{[1
]}

GEITNER, KA ^{[1
]}

JACK, ML ^{[1
]}

DIXON, WR ^{[1
]}

KAPLAN, SA ^{[1
]}

机构：

[1] HOFFMANN LA ROCHE INC,DEPT BIOCHEM & DRUG METAB,NUTLEY,NJ 07110

来源：

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS | 1977年 / 5卷 / 01期

关键词：

D O I：

10.1007/BF01064807

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：25 / 39

页数：15

共 18 条

[1] GENERAL TREATMENT OF LINEAR MAMMILLARY MODELS WITH ELIMINATION FROM ANY COMPARTMENT AS USED IN PHARMACOKINETICS [J].

BENET, LZ .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1972, 61 (04) :536-&

[2] STATISTICAL ESTIMATIONS IN PHARMACOKINETICS [J].

BOXENBAU.HG ;

RIEGELMA.S ;

ELASHOFF, RM .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1974, 2 (02) :123-148

[3] PHARMACOKINETIC AND BIO-PHARMACEUTIC PROFILE OF CHLORDIAZEPOXIDE HCL IN HEALTHY SUBJECTS - SINGLE-DOSE STUDIES BY INTRAVENOUS, INTRAMUSCULAR, AND ORAL ROUTES [J].

BOXENBAUM, HG ;

GEITNER, KA ;

JACK, ML ;

DIXON, WR ;

SPIEGEL, HE ;

SYMINGTON, J ;

CHRISTIAN, R ;

MOORE, JD ;

WEISSMAN, L ;

KAPLAN, SA .

JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1977, 5 (01) :3-23

[4]

DIXON R, 1976, CLIN PHARMACOL THER, V20, P450

[5] RELATIONSHIP BETWEEN DRUG CONCENTRATION IN PLASMA OR SERUM AND AMOUNT OF DRUG IN BODY [J].

GIBALDI, M ;

NAGASHIMA, R ;

LEVY, G .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1969, 58 (02) :193-+

[6]

GOLDSTEIN A, 1964, BIOSTATISTICS INTROD, P59

[7] HEPATIC VASCULAR BED [J].

GREENWAY, CV ;

STARK, RD .

PHYSIOLOGICAL REVIEWS, 1971, 51 (01) :23-+

[8] PHARMACOKINETIC MODEL FOR CHLORDIAZEPOXIDE HCL IN DOG [J].

KAPLAN, SA ;

LEWIS, M ;

SCHWARTZ, MA ;

POSTMA, E ;

COTLER, S ;

ABRUZZO, CW ;

LEE, TL ;

WEINFELD, RE .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1970, 59 (11) :1569-&

[9]

Metzler C.M., 1974, USERS MANUAL NONLIN

[10]

Randall L.O., 1973, BENZODIAZEPINES, P27

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