SPARTEINE OXIDATION IS PRACTICALLY ABOLISHED IN QUINIDINE-TREATED PATIENTS

被引：71
作者：
BRINN, R
BROSEN, K
GRAM, LF
HAGHFELT, T
OTTON, SV
机构：
[1] ODENSE UNIV,SCH MED,DEPT CLIN PHARMACOL,JB WINSLOWS VEJ 19,DK-5000 ODENSE C,DENMARK
[2] ODENSE UNIV,SCH MED,DEPT CARDIOL,DK-5000 ODENSE C,DENMARK
来源：
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1986年 / 22卷 / 02期
关键词：
D O I：
10.1111/j.1365-2125.1986.tb05250.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：194 / 197
页数：4
相关论文
共 19 条
[1]  
BOOBIS AR, 1983, MOL PHARMACOL, V23, P474
[2]  
BROSEN K, 1985, ACTA PHARMACOL TOX, V57, P357
[3]   GENETICALLY-DETERMINED VARIABILITY IN ACETYLATION AND OXIDATION - THERAPEUTIC IMPLICATIONS [J].
CLARK, DWJ .
DRUGS, 1985, 29 (04) :342-375
[4]   THE GENETIC-CONTROL OF BUFURALOL METABOLISM IN MAN [J].
DAYER, P ;
BALANT, L ;
COURVOISIER, F ;
KUPFER, A ;
KUBLI, A ;
GORGIA, A ;
FABRE, J .
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 1982, 7 (01) :73-77
[5]   INTER-ETHNIC DIFFERENCE IN SPARTEINE OXIDATION AMONG GHANAIANS AND GERMANS [J].
EICHELBAUM, M ;
WOOLHOUSE, NM .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1985, 28 (01) :79-83
[6]   A FAMILY AND POPULATION STUDY OF THE GENETIC-POLYMORPHISM OF DEBRISOQUINE OXIDATION IN A WHITE BRITISH-POPULATION [J].
EVANS, DAP ;
MAHGOUB, A ;
SLOAN, TP ;
IDLE, JR ;
SMITH, RL .
JOURNAL OF MEDICAL GENETICS, 1980, 17 (02) :102-105
[7]   PHARMACOGENETICS OF MEPHENYTOIN - A NEW DRUG HYDROXYLATION POLYMORPHISM IN MAN [J].
KUPFER, A ;
PREISIG, R .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 26 (06) :753-759
[8]   SINGLE-DOSE QUINIDINE TREATMENT INHIBITS METOPROLOL OXIDATION IN EXTENSIVE METABOLIZERS [J].
LEEMANN, T ;
DAYER, P ;
MEYER, UA .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1986, 29 (06) :739-741
[9]   THE RELATIONSHIP BETWEEN DEBRISOQUINE OXIDATION PHENOTYPE AND THE PHARMACOKINETICS AND PHARMACODYNAMICS OF PROPRANOLOL [J].
LENNARD, MS ;
JACKSON, PR ;
FREESTONE, S ;
TUCKER, GT ;
RAMSAY, LE ;
WOODS, HF .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 17 (06) :679-685
[10]   OXIDATION PHENOTYPE - A MAJOR DETERMINANT OF METOPROLOL METABOLISM AND RESPONSE [J].
LENNARD, MS ;
SILAS, JH ;
FREESTONE, S ;
RAMSAY, LE ;
TUCKER, GT ;
WOODS, HF .
NEW ENGLAND JOURNAL OF MEDICINE, 1982, 307 (25) :1558-1560
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