AN UNUSUAL ROUTE TO POTENTIAL PLATINUM ANTITUMOR COMPOUNDS - SYNTHESIS, REACTIVITY, AND SPECTROSCOPIC PROPERTIES OF THE PT-IV COMPLEX FAC-[PTCL3(NH3)(2)L]CL

被引:0
|
作者
BIERBACH, U
REEDIJK, J
机构
[1] Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden University, Leiden, NL-2300 RA
来源
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1994年 / 33卷 / 15-16期
关键词
D O I
10.1002/anie.199416321
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Oxidative addition to the antitumor agent cisplatin yields the PtIV complex 1, in which 1,1,3,3‐te‐tramethylthiourea is coordinated to platinum. The structure was determined primarily by impressive high‐resolution 1H and 195Pt NMR experiments and by analysis of the IR spectrum. (Figure Presented.) Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany
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页码:1632 / 1634
页数:3
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