INHIBITION OF PLATELET AND NEUTROPHIL PHOSPHOLIPASE-A2 BY HYDROXYEICOSATETRAENOIC ACIDS (HETES) - A NOVEL PHARMACOLOGICAL MECHANISM FOR REGULATING FREE FATTY-ACID RELEASE

被引:73
作者
CHANG, J
BLAZEK, E
KREFT, AF
LEWIS, AJ
机构
关键词
D O I
10.1016/0006-2952(85)90701-4
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:1571 / 1575
页数:5
相关论文
共 26 条
[1]   MARKED INCREASE OF HUMAN-PLATELET PHOSPHOLIPASE-A2 ACTIVITY INVITRO AND DEMONSTRATION OF AN ENDOGENOUS INHIBITOR [J].
BALLOU, LR ;
CHEUNG, WY .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (17) :5203-5207
[2]  
BALLOU LR, 1984, FEDERATION P, V43, P1463
[3]   DIGLYCERIDE LIPASE - PATHWAY FOR ARACHIDONATE RELEASE FROM HUMAN-PLATELETS [J].
BELL, RL ;
KENNERLY, DA ;
STANFORD, N ;
MAJERUS, PW .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (07) :3238-3241
[4]   SELECTIVE RELEASE OF ARCHIDONIC ACID FROM PHOSPHOLIPIDS OF HUMAN PLATELETS IN RESPONSE TO THROMBIN [J].
BILLS, TK ;
SMITH, JB ;
SILVER, MJ .
JOURNAL OF CLINICAL INVESTIGATION, 1977, 60 (01) :1-6
[5]   METABOLISM OF (C-14) ARACHIDONIC-ACID BY HUMAN PLATELETS [J].
BILLS, TK ;
SMITH, JB ;
SILVER, MJ .
BIOCHIMICA ET BIOPHYSICA ACTA, 1976, 424 (02) :303-314
[6]   DISTRIBUTION AND METABOLISM OF ARACHIDONIC-ACID IN RABBIT PLATELETS DURING AGGREGATION AND ITS MODIFICATION BY DRUGS [J].
BLACKWELL, GJ ;
DUNCOMBE, WG ;
FLOWER, RJ ;
PARSONS, MF ;
VANE, JR .
BRITISH JOURNAL OF PHARMACOLOGY, 1977, 59 (02) :353-366
[7]   NEW CONCEPTS IN THE MODULATION OF LEUKOTRIENE SYNTHESIS [J].
BORGEAT, P ;
DELACLOS, BF ;
MACLOUF, J .
BIOCHEMICAL PHARMACOLOGY, 1983, 32 (03) :381-387
[8]  
BROCKMAN HJ, 1980, J CLIN INVEST, V66, P275
[9]  
DARKSON S, 1975, J BIOL CHEM, V250, P9342
[10]   CHARACTERISTICS OF LEUKOTRIENE (LT) AND HYDROXY EICOSATETRAENOIC ACID (HETE) SYNTHESIS IN HUMAN-LEUKOCYTES INVITRO - EFFECT OF ARACHIDONIC-ACID CONCENTRATION [J].
DELACLOS, BF ;
BRAQUET, P ;
BORGEAT, P .
PROSTAGLANDINS LEUKOTRIENES AND MEDICINE, 1984, 13 (01) :47-52