H-1-NMR AND C-13-NMR ASSIGNMENTS FOR SOME PYRROLO[2,1B]-QUINAZOLINE ALKALOIDS OF ADHATODA-VASICA

From the leaves of Adhatoda vasica, the pyrrolo[2,1b]quinazoline alkaloids l-vasicine [1], l-vasicinone [2], l-vasicol [3], anisotine [7], 3-hydroxyanisotine [8], and a new alkaloid, vasnetine [9] have been isolated and their structures established by H-1- and C-13-nmr spectral studies. The chemical shift assignments for these alkaloids were confirmed by H-1 homonuclear COSY, DEFT, HETCOR, selective INEPT and HMBC nmr experiments.