APIOSPORAMIDE, A NEW ANTIFUNGAL AGENT FROM THE COPROPHILOUS FUNGUS APIOSPORA-MONTAGNEI

被引：82

作者：

ALFATAFTA, AA

GLOER, JB

SCOTT, JA

MALLOCH, D

机构：

[1] UNIV IOWA,DEPT CHEM,IOWA CITY,IA 52242

[2] UNIV TORONTO,DEPT BOT,TORONTO,ON M5S 1A1,CANADA

来源：

JOURNAL OF NATURAL PRODUCTS-LLOYDIA | 1994年 / 57卷 / 12期

关键词：

D O I：

10.1021/np50114a012

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Bioassay-guided fractionation of an EtOAc extract from the mycelium of the coprophilous fungus Apiospora montagnei has furnished a new antifungal metabolite, named apiosporamide [1], and the known dihydroisocoumarin cis-(3R,4R)-4-hydroxymellein [4]. The structure of 1 was assigned on the basis of HMBC, HMQC, NOESY, and hrms data. Elucidation of the structure was complicated by the fact that several nmr signals appeared only under certain conditions.

引用

页码：1696 / 1702

页数：7

共 20 条

[1]

ALFATAFTA AA, 1994, THESIS U IOWA IOWA C, P53

[2] SENSITIVITY-ENHANCED TWO-DIMENSIONAL HETERONUCLEAR SHIFT CORRELATION NMR-SPECTROSCOPY [J].