INFREQUENT NEONATAL OPIATE WITHDRAWAL FOLLOWING MATERNAL METHADONE DETOXIFICATION DURING PREGNANCY

被引：65
作者：
MAAS, U [1 ]
KATTNER, E [1 ]
WEINGARTJESSE, B [1 ]
SCHAFER, A [1 ]
OBLADEN, M [1 ]
机构：
[1] FREE UNIV BERLIN,UNIV HOSP RUDOLF VIRCHOW,WOMENS CLIN,W-1000 BERLIN 33,GERMANY
来源：
JOURNAL OF PERINATAL MEDICINE | 1990年 / 18卷 / 02期
关键词：
Drogenabhängigkeit; Drug addiction; heroin dependence; Heroinabhängigkeit; Methadon-Substitutionsprogramm; methadone substitution; neonatal abstincenc; neonatal opiate; neonataler Drogenentzug; Opiat-Entzugssyndrom des Neugeborenen; withdrawal;
D O I：
10.1515/jpme.1990.18.2.111
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
The influence of maternal participation in a methadone detoxification program as compared to street drug use on intrauterine growth and neonatal morbidity was analysed in 75 newborns. — 58 of 75 pregnant addicts joined the methadone program in 17 women with successful prepartal detoxification, we found a longer course of pregnancy as well as normalized birth weight, head circumference and resporatory status of the neonates. The HIV-status showed no influence on prenatal growth. 63% of all infants developed a neonatal abstinence syndrome; this incidence was lower after maternal participation in the methadone detoxification program: 55 vs. 88%, p < 0.05. Postnatal respiratory insufficiency occurred more frequently after methadone exposure than after heroin exposure before birth (p < 0.05). © 1990, Walter de Gruyter. All rights reserved.
引用
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页码：111 / 118
页数：8
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