Basal Cell Carcinoma of the Head and Neck Region in Ethnic Chinese

被引:7
作者
Chow, Velda Ling Yu [1 ]
Chan, Jimmy Yu Wai [1 ]
Chan, Richie Chiu Lung [1 ]
Chung, Joseph Hon Ping [1 ]
Wei, William Ignace [1 ]
机构
[1] Univ Hong Kong, Div Head & Neck Plast & Reconstruct Surg, Dept Surg, Queen Mary Hosp, Pokfulam Rd, Hong Kong, Hong Kong, Peoples R China
关键词
D O I
10.1155/2011/890908
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objectives. This study aims to report our experience in the management of HNBCC in ethnic Chinese over a 10-year period. Methods. A retrospective review of all ethnic Chinese patients with HNBCC treated in a tertiary centre from 1999 to 2009. Results. From 1999 to 2009, 225 patients underwent surgical excision for HNBCC. Majority were elderly female patients. Commonest presentation was a pigmented (76.2%) ulcer (64.8%) over the nose (31.6%). Median skin margin taken on tumour excision was 2.0 mm; primary skin closure was achieved in 51.8%. Postresection skin margin was clear in 75.4%. Of those with inadequate skin margins, 56.7% opted for further treatment, 43.4% for observation. Recurrence rates were 2.6% and 13.8%, respectively (P = 0.106). Overall recurrence rate was 5.5%. Conclusions. HNBCC commonly presented as pigmented ulcers over the nose of elderly female patients in our locality. Adequate tumour excision +/- reconstruction offered the best chance of cure. Reexcision of those with inadequate skin margins improved local tumour control.
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页数:7
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