Flatbush Diabetes: A Report of Two Cases and a Review of the Literature

被引:0
作者
Gul, Ozen Oz [1 ]
Guclu, Metin [1 ]
Tuncel, Ercan [1 ]
Imamogly, Sazi [1 ]
机构
[1] Uludag Univ Med Sch, Dept Endocrinol & Metab, Bursa, Turkey
关键词
Flatbush diabetes; prone to ketosis; classification of diabetes mellitus;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Type 2 diabetes is an endocrine and metabolic disorder appearing with insulin resistance and impaired beta cell secretory function. Type 1 diabetes is characterized by the autoimmune destruction of pancreatic beta cells, which leads to absolute insulin deficiency. Diabetic ketoacidosis is considered a cardinal feature of type 1 diabetes. A number of studies have demonstrated that diabetic ketoacidosis also occurs in subjects with type 2 diabetes. Such patients are classified as idiopathic type 1 diabetes, type 1B diabetes, Flatbush diabetes or ketosis-prone type 2 diabetes. The aim of our study was to present two patients, who were diagnosed with ketosis-prone type 2 DM, as well as to discuss the subject in the light of the extant literature and to be able to make general recommendations.
引用
收藏
页码:56 / 59
页数:4
相关论文
共 28 条
[1]   KETOACIDOSIS-ONSET NONINSULIN-DEPENDENT DIABETES IN JAPANESE SUBJECTS [J].
AIZAWA, T ;
KATAKURA, M ;
TAGUCHI, N ;
KOBAYASHI, H ;
AOYAGI, E ;
HASHIZUME, K ;
YOSHIZAWA, K .
AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 1995, 310 (05) :198-201
[2]   Long-term normoglycemic remission in black newly diagnosed NIDDM subjects [J].
Banerji, MA ;
Chaiken, RL ;
Lebovitz, HE .
DIABETES, 1996, 45 (03) :337-341
[3]   GAD ANTIBODY NEGATIVE NIDDM IN ADULT BLACK SUBJECTS WITH DIABETIC-KETOACIDOSIS AND INCREASED FREQUENCY OF HUMAN-LEUKOCYTE ANTIGEN DR3 AND DR4 - FLATBUSH DIABETES [J].
BANERJI, MA ;
CHAIKEN, RL ;
HUEY, H ;
TUOMI, T ;
NORIN, AJ ;
MACKAY, IR ;
ROWLEY, MJ ;
ZIMMET, PZ ;
LEBOVITZ, HE .
DIABETES, 1994, 43 (06) :741-745
[4]   REMISSION IN NON-INSULIN-DEPENDENT DIABETES-MELLITUS - CLINICAL CHARACTERISTICS OF REMISSION AND RELAPSE IN BLACK PATIENTS [J].
BANERJI, MA ;
LEBOVITZ, HE .
MEDICINE, 1990, 69 (03) :176-185
[5]  
Gavin JR, 1997, DIABETES CARE, V20, P1183
[6]   Small doses of subcutaneous insulin as a strategy for preventing slowly progressive beta-cell failure in islet cell antibody-positive patients with clinical features of NIDDM [J].
Kobayashi, T ;
Nakanishi, K ;
Murase, T ;
Kosaka, K .
DIABETES, 1996, 45 (05) :622-626
[7]   TIME COURSE OF ISLET CELL ANTIBODIES AND BETA-CELL FUNCTION IN NON-INSULIN-DEPENDENT STAGE OF TYPE-I DIABETES [J].
KOBAYASHI, T ;
ITOH, T ;
KOSAKA, K ;
SATO, K ;
TSUJI, K .
DIABETES, 1987, 36 (04) :510-517
[8]   Ketosis-prone diabetes:: Dissection of a heterogeneous syndrome using an immunogenetic and β-cell functional classification, prospective analysis, and clinical outcomes [J].
Maldonado, M ;
Hampe, CS ;
Gaur, LK ;
D'Amico, S ;
Iyer, D ;
Hammerle, LP ;
Bolgiano, D ;
Rodriguez, L ;
Rajan, A ;
Lernmark, Å ;
Balasubramanyam, A .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (11) :5090-5098
[9]  
Maldonado MR, 2004, ETHNIC DIS, V14, P243
[10]   Ketosis-prone type 2 diabetes in patients of sub-Saharan African origin -: Clinical pathophysiology and natural history of β-cell dysfunction and insulin resistance [J].
Mauvais-Jarvis, F ;
Sobngwi, E ;
Porcher, R ;
Riveline, JP ;
Kevorkian, JP ;
Vaisse, C ;
Charpentier, G ;
Guillausseau, PJ ;
Vexiau, P ;
Gautier, JF .
DIABETES, 2004, 53 (03) :645-653